View Dr Saso's business profile at Care Oncology LLC. Marsden founded the Royal Free Hospital and the Royal Marsden in Chelsea, both as a direct result of his personal experiences. Radovan SASO of The Royal Marsden NHS Foundation Trust, London | Read 97 publications | Contact Radovan SASO Dr. Dr Justin Grayer Principal Psychologist/ Team Lead at The Royal Marsden NHS Foundation Trust London, United Kingdom 396 connections Na susretu će govoriti Ljiljana Pomer, predstavnica udruge MijelomCRO, dr. Radovan Saso iz bolnice Royal Marsden u Londonu, zatim doc. Bone marrow transplant (BMT) was performed in 191 patient, while 684 patients had peripheral blood stem cell transplant (SCT). August 1, 2019 August 13, 2019 admin Aktivnosti. Maria Ifijen | London, United Kingdom | Specialty Doctor ( Medical Oncology) at The Royal Marsden NHS Foundation Trust | 35 connections | View Maria's homepage, profile, activity, articles The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. We offer proven treatments including cytotoxic chemotherapy, immunotherapy (such as antibodies that bind to and kill malignant cells), enzyme inhibiting drugs (such as tyrosine kinase inhibitors) and bone marrow transplantation. Nana Benson-Quarm. Consultant Hepatobiliary and Robotic surgeon at the world renowned Royal Marsden Hospital. Some authors have suggested that RIC allo-SCT be performed entirely in the outpatient setting. dr. Lejla Ibričević iz UKC Sarajevo, Nerma Mrđanović predstavnica udruge Mijelom u BiH te naša Ljiljana Pomper. One hundred and nineteen patients with acute myeloid leukemia in first remission underwent non-T cell-depleted marrow allografts from HLA-identical siblings after TBI and cyclophosphamide (n = 72) or melphalan (n = 47). The purpose of the study was to determine the role of sequential therapy (ST) in new patients with myeloma presenting with renal dysfunction (RD): serum creatinine >140 µmol/L (1.6 mg/dL). S godišnjeg skupa Global Myeloma Action Network. Royal Marsden Hospital and the Institute of Cancer Research, Sutton, UK . The underlying pathophysiologic phenomena of the clinical features include suppression of humoral- and cell-mediated immunity, elevation of IL-6, abnormalities of the bone marrow microenvironment, and increased … Coronavirus (COVID-19) latest: Visiting The Royal Marsden is still suspended, but we want to reassure our patients, their families and anyone worried about cancer during this difficult time that we are still delivering treatment - the hospital is open. Between March 1973 and August 2003, 747 patients (M: 430, F:317; median age: 29yr, range:1–65) who survived for at least 1 yr. post stem cell transplant and were 15 to 65 years of age (median: 38, range:15–71) at the time of last follow-up (LFU) were analysed to study the incidence and outcome of pregnancies. A low CD34+ cell dose results in higher mortality and poorer survival after blood or marrow stem cell transplantation from HLA-identical siblings: Should 2 x 106 CD34+ cells/kg be considered the minimum threshold? Faith Davies earned her medical degree from the University of Wales College of Medicine and completed her general medical training and hematology specialty training in the United Kingdom. This trust provides Oncology - Medical at 2 hospital(s) Please note: this consultant may not be available at all these locations. Addressed mainly to the Nursing Profession Dr Adam Sharp is Leader of the Translational Therapeutics Team and Honorary Consultant Medical Oncologist within the Prostate Cancer Targeted Therapies Group and Drug Development Unit at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust.. Multiple myeloma is a malignant disease characterized by plasmacytosis, paraprotein production, bone lesions, hypercalcemia, susceptibility to infections, and renal impairment. 100 adults with ALL in CR1 received melphalan 110 mg/m2 with TBI followed by marrow (n=35) or melphalan 200 mg/m2 followed by blood stem cells (n=65) between 7/1984 and 2/2003. Only verified researchers can join ResearchGate and send messages to other members. Born in Sheffield in 1796, Marsden moved to London in 1816. You can write a book review and share your experiences. High dose melphalan with ASCT has formed an integral part of the treatment of younger p... Hiwarkar P, Shaw BE, Tredger JM, Brown NW, Kulkarni S, Saso R, Evans S, Treleaven J, Davies FE, Ethell ME, Morgan GJ, Potter MN. PET and MRI scans to stage many lymphomas and myelomas. Correspondence: Dr Estella Matutes, C/Bruc, N: 25, 1st floor, Barcelona 08010, Spain. Absence of N-RAS point mutations in peripheral blood cells of patients with aplastic anaemia and paroxysmal nocturnal haemoglobinurea, The novel monoclonal antibody By114 helps detect the early emergence of a paroxysmal nocturnal hemoglobinuria clone in aplastic anemia, Autoimmune hemolytic anemia in chronic lymphocytic leukemia, [Hairy cell leukemia. Nadia YOUSAF, Consultant Medical Oncologist of The Royal Marsden NHS Foundation Trust, London | Read 63 publications | Contact Nadia YOUSAF And when people entrust their lives to us, they have the right to. Dr Nicholas Van As qualified in medicine in 1995 in South Africa and completed specialist training in clinical oncology at Guy’s and St Thomas’ Hospital, The Royal Marsden and The Institute of Cancer Research. Vallari Shah. The median leukocyte and platelet count at presentation were 16.5x109/1 (range:1.7-391) and 124 x 109/1 (range:7-427) respectively. The overall i... 1348 Barbara J Bain. Instinctively, most clinicians may switch treatment, particularly since the advent of new drugs for the treatment of myeloma. May 2004; Michael Gattens. The unit diagnoses and treats a wide range of blood cancers: We use an integrated approach to diagnose blood cancers using multiple tests on blood, bone marrow and lymph node samples. In a series of 48 patients with splenic marginal zone lymphoma (SMZL) with circulating villous lymphocytes, we describe the clinical and laboratory features of nine cases that transformed to high-grade B-cell lymphoma. Dr Rao is a Consultant Medical Oncologist specializing in gastrointestinal cancers and cancers of unknown primary within the Gastrointestinal Unit at the Royal Marsden Hospital. Diagnosis was made on the basis of FAB criteria. The purpose of the study was to determine the role of sequential therapy (ST) in new patients with myeloma presenting with renal dysfunction (RD): serum creatinine >140 micromol/L (1.6 mg/dL). S godišnjeg skupa Global Myeloma Action Network. About us . The combination of bortezomib (velcade), pulsed dexamethasone and weekly cyclophosphamide (CVD) in relapsed/refractory myeloma patients induces high overall (75%) and complete (31%) response rates compared to velcade/dexamethasone (overall 47%, CR 5%) and velcade alone (overall 27%, CR 0%). Export . Median duration of survival from diagnosis of MDS/AML was 10 months and six patients died. Lenolidamide (Revlimid), in Combination with Cyclophosphamide and Dexamethasone (CRD) Is an Effective Regimen for Heavily Pre-Treated Myeloma Patients. https://www.icr.ac.uk/our-research/researchers-and-teams/dr-nicholas-van-as Median follow-up after transplant is 27 months, and 13 patients are currently alive. Lymphocyte Count on Day 56 Predicts for Reduced Risk of Infection Related Mortality Following Non-Myeloablative Allogeneic Haematopoietic Stem Cell Transplantation. SPS developed in 31 patients a median of 10 months after transplantation (range, 3 to 187 months). R Saso, 1 S Kulkarni, 2 P Mitchell, 3 J Treleaven, 1 G J Swansbury, 4 J Mehta, 5 R Powles, 2 S Ashley, 6 R Kuan, 7 and T Powles 2 1 Departments of Haematology, 2 Medical Oncology, 4 Cytogenetics, 7 Statistics, The Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK Clin Transplant 2011: 25: 222–227. https://www.icr.ac.uk/our-research/researchers-and-teams/dr-samra-turajlic Addition of lomustine (ccnu) to standard daunorubicin-cytarabine (3+7) for induction of remission in acute myeloid leukaemia patients over 50 years. Sequential Development of Myelodysplasia and Acute Myeloid Leukemia but with no Karyotypic Evolution after Autografting in a Patient with Philadelphia Positive Acute Lymphoblastic Leukemia, How Erythropoietin Affects Bone Marrow of Uremic Patients, Idarubicin, high-dose cytarabine, and etoposide for induction of remission in acute leukemia, Transfusion requirements after bone marrow transplantation from HLA-identical siblings: Effects of donor-recipient ABO incompatibility. Seventeen newly diagnosed patie... As there is concern regarding the high carcinogenic potential of melphalan (Mel), 725 patients with haematological malignancies who received allogeneic (n = 714) or syngeneic (n = 11) transplants over the last 26 years were followed-up to evaluate if melphalan was more likely to result in secondary malignant neoplasms (SMNs) than cyclophosphamide (... Forty healthy adult donors underwent marrow (BM) as well as peripheral blood (PBSC) stem cell collections for their HLA-identical adult siblings with hematologic malignancies. Kirsty MORRISON of The Royal Marsden NHS Foundation Trust, London | Read 7 publications | Contact Kirsty MORRISON Sorry, you need to be a researcher to join ResearchGate. The development of high dose melphalan and of autologous bone marrow transplantation in the treatment of multiple myeloma: Royal Marsden and St Bartholomew's Hospital studies. The bone marrow showed a median of 50% blasts (range: 11 -9... Primary therapy with 140 mg/m² melphalan without rescue results in high response rates in myeloma with very long-term survival in some patients (Powles et al. Due to our privacy policy, only current members can send messages to people on ResearchGate. The myelodysplastic syndromes (MDS) have a significant frequency of evolution into acute myeloid leukaemia (AML). MijelomCRO je na susretu u Amsterdamu podijelila informacije o … 1291 patients with myeloma were registered on the Royal Marsden Hospital Database in the period between 1981–2009, of which 875 patients underwent autologous transplantation. For the Royal Marsden deputy chief executive Liz Bishop, nursing is in the blood. 1. The Ambulatory Care Service allows some patients undergoing relatively intensive therapies to receive some of their care without needing admission overnight. In all, 451 myeloma patients, 51% previously untreated, underwent elective single autotransplantation after 200 mg/m(2) melphalan between 1985 and 2001 at the Royal Marsden Hospital. 24 Outcome of teenagers and young adults with ependymoma: the Royal Marsden experience. In Chelsea, NHS and private patients for chemotherapy and autologous transplants are admitted onto Wiltshaw Ward. Other readers will always be interested in your opinion of the books you've read. With your help we can continue to be there for everyone who needs us. 2009 Sep;25(9):1047-52. Search the NHS website Search. 2. Na susretu će govoriti Ljiljana Pomer, predstavnica udruge MijelomCRO, dr. Radovan Saso iz bolnice Royal Marsden u Londonu, zatim doc. Search for more papers by this author. Sheela RAO, Consultant of The Royal Marsden NHS Foundation Trust, London | Read 188 publications | Contact Sheela RAO He was a winner of the NHS Innovator Award in 2006 for the introduction of new … Search for more papers by this author. Coronavirus (COVID-19) latest: Visiting The Royal Marsden is still suspended, but we want to reassure our patients, their families and anyone worried about cancer during this difficult time that we are still delivering treatment - the hospital is open. August 1, 2019 August 13, 2019 admin Aktivnosti. Induction chemotherapy followed by high-dose melphalan (HDM) is the standard treatment for fitter patients with myeloma. Splenomegaly is the main clinical manifestation,... Join ResearchGate to find the people and research you need to help your work. Coping with hydrological extremes (Mitigation and Adaptation Strategies for Global Change (2003) 7:3). Dr at The Royal Marsden NHS Foundation Trust Sutton, United Kingdom 20 connections. Nationally recognised as the definitive guide to clinical nursing skills, The Royal Marsden Manual of Clinical Nursing Procedures has provided essential nursing knowledge and up-to-date information on nursing skills and procedures for over 30 years. Using this strate... A total of 81 adults with acute myeloid leukemia (AML) (47% favorable karyotypes) were autografted in first remission after melphalan-total body irradiation, having received 0 (n=7), 1 (n=19), 2 (n=51), or 3 (n=4) consolidation chemotherapy cycles before harvest. Collection of peripheral blood stem cells in newly diagnosed myeloma patients without any prior cytoreductive therapy: The first step towards an 'operational cure'? Early high resolution computed tomography (HRCT) scans allow for prompt diagnosis and more efficacious treatment of invasive pulmonary aspergillosis (IPA) in immunocompromised patients with haematologic malignancies. Coronavirus (COVID-19) latest: Visiting The Royal Marsden is still suspended, but we want to reassure our patients, their families and anyone worried about cancer during this difficult time that we are still delivering treatment - the hospital is open. This study was conducted to compare the presenting features and outcome of newly-diagnosed myeloma with and without extramedullary (EM) manifestations and to determine the optimum treatment. Dr R. Saso’s HQ phone number is (605) 716-3200 What is Dr R. Saso’s latest job experience? Saso et al 1. We're here to support GPs in identifying the signs of cancer and ensuring patients are referred at the right time. We report two cases of AML who presented with well-characterised cytogenetic abnormalities at presentation: t(8;21) and t(15;17) respectively, and who, after achieving complete morphological and cytogenetic remissions post-autograft, deve... Deficient expression of glycosylphosphatidyl inositol (GPI)-anchored proteins in aplastic anaemia (AA) patients has previously been reported to be associated with a poor response to immunosuppressive (IS) therapy. Dr Ian Chau Consultant Medical Oncologist The Royal Marsden Hospital London & Surrey. The infection was fatal in 7 patients. Email Finder Top Companies Company Search People Search Solutions About Us. We also work on new ways to improve diagnosis of these diseases. This model is based on an intention to treat analysis of 383 patients with previously untreated myeloma, their responses to induction chemotherapy and to intensive high dose melphalan (HDM). Moreno L, Bautista FJ, Zacharoulis S. Childs Nerv Syst. Ana Marín‐Niebla. 31, 49-50. We believe research is one of the key factors in improving patient outcomes. Endometrial cancer is the most common gynaecological cancer in the USA and as the authors have pointed out the incidence in the UK is increasing 1. Between April 1985 and June 1998, 251 patients, 59 (23%) with RD were entered into a ST program comprised of infusional chemotherapy (IC) with VAMP/C-VAMP (v... ABLC (Abelcet, The Liposome Company) is a ribbon-shaped liposomal formulation of amphotericin B consisting of dimyristoyl-phosphatidylcholine and dimyristoylphosphatidylglycerol in a 7:3 molar ratio which is especially concentrated in pulmonary tissue. The Natural History of Myeloma Patients Who Relapse Early After High Dose Therapy. Leuk: 182, other: 223). The Haemato-oncology Unit offers state-of-the-art diagnosis and treatment of all haemato-oncology and lymphatic disorders. Between 8/85 and 6/98, 144 newly diagnosed myeloma patients with a median age of 53 years (range, 31-72) received infusional chemot... Of the 61 newly diagnosed patients with Bence-Jones (BJ) myeloma presenting to our centre between May 1986 and December 1997, 53 received sequential therapy (ST) comprising infusional chemotherapy (IC) followed by high-dose therapy and autotransplantation with interferon-alpha2b maintenance. Correspondence: Dr JG Treleaven, Department of Haematology, Royal Marsden NHS Trust, Downs Road, Sutton, Surrey SM2 5PT, UK Received 29 July 1998; accepted 11 October 1998 There has been an improvement in the population based survival of patients with MM in the UK (Office of National Statistics), however, because of the way the data is collected it is uncertain what has happened to the outcome of younger patients. Coronavirus (COVID-19): visiting The Royal Marsden suspended . Home Health A-Z Live Well Care and support Pregnancy NHS services The Royal Marsden Hospital (Surrey) 020 8642 6011 … The median nucleated (7.0 vs 3.2 x 10(8)/kg; P < 0.000... Of 1774 patients with breast cancer given mitoxantrone (MTZ) with methotrexate (n = 492) or with methotrexate and mitomycin C (n = 1282), nine developed MDS/AML after a median of 2.5 years. Menu. CAR T-cells and Cellular Therapy London. Dr Mark Ethell, Consultant in Haematology and Bone Marrow Transplantation, Dr Chloe Anthias, Consultant in Haematology and Bone Marrow Transplantation, Dr Sandra Easdale, Locum Consultant in Haematology and Bone Marrow Transplantation, Dr Ayoma Attygalle, Consultant Haematopathologist, Dr Corinne De Lord, Consultant Haematologist, Kim Davis, Haemato-Oncology Research Sister, Joy Brennan, Stem Cell Transplant Co-ordinating Sister, Maria Mulligan, Stem Cell Transplant Co-ordinator, Hayley Leonard, Anthony Nolan Post-Transplant Nurse Specialist, Mucha Mupanemunda, Leukaemia Nurse Specialist, Sharon West, Haemato-oncology Advanced Nurse Practitioner, Carmela (Ella) Panlaqui, Myeloma Nurse Specialist, Michelle Harris, Lymphoma Nurse Specialist, Lucy Whiteman, Lymphoma/CLL Nurse Specialist, Kathryn Chandler, Lymphoma Nurse Specialist, Jane Howes, Haemato-oncology Clinical Nurse Specialist, Sarah Thompson, Haemato-oncology Advanced Nurse Practitioner, Richard Spencer, Haemato-oncology Advanced Nurse Practitioner. , while 684 patients had peripheral blood Stem Cell transplantation Pomer, predstavnica udruge Mijelom u BiH te Ljiljana. 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